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to study the safety and efficacy of the newer biological
DMARDs in RA and SLE. Recently, the trials of coxibs are
concentrating on cardiovascular outcomes to a greater
extent than their gastr-toxicity. We have also been looking
at SLE genetics in collaboration with the Hepatology, with
particular reference to the Vitamin D receptor and its role
in the pathogenesis of auto-immune diseases. Newer areas
of research include the study of chronic tophaceous GOUT;
community aspects of diagnosing and treating rheumatic
diseases at Community Health Centres; early rheumatoid
arthritis; genetics of bone loss in SLE; and functional
problems in ankylosing spondylitis.
Divisional Statistics
Permanent and Long-term Contract Staff
Senior Lecturer
Research Staff
Nurse practitioner
Administrative and Clerical staff
Honorary Staff
Honorary Lecturers
Rotating Medical Registrar
Medical Officer
Contact Details
Postal Address:
J47 Old Main Building,
Groote Schuur Hospital,
Observatory 7925
Telephone: +27 21 404 5422/2131 or 406 6514
Fax: +27 21 448 3253
Department of Medicine
Research output
Chapters in books
Barnes, K.I. 2012. Antimalarial drugs and the control and
elimination of malaria. In H.M Staines and S. Krishna (eds),
Treatment and Prevention of Malaria: Antimalarial Drug
Chemistry, Action and Use, pp. 1-17. London: Springer
Science & Business Media B.V. ISBN 9873034604796.
Bekker, L., Beyrer, C. and Quinn, T. 2012. Behavioral and
Biomedical combination strategies for HIV Prevention. In
F. Bushman, G. Nabel, and R. Swanstrom (eds), HIV: From
biology to prevention and treatment, pp. 537-559. New
York: Cold Spring Harbor Lab Press. ISBN 9781936113408.
Blumberg, L., Cohen, C. and Barnes, K.I. 2012. Malaria.
In M. Kibel, H. Saloojee and T. Westwood (eds), Child
Health for All, pp. 404-411. 5th edition. Cape Town: Oxford
University Press Southern Africa. ISBN 9780199042357.
Mazandu, G.K. and Mulder, N.J. 2012. Enhancing drug
target identification in mycobacterium tuberculosis. In S.E.
Walker and D.F. Martin (eds), Tuberculosis: Risk Factors,
Drug Resistance and Treatment, pp.181-209. New York:
Nova Biomedical. ISBN 9781620819913.
Okombo, J., Mwai, L. and Nzila, A. 2012. Tackling the
problem of antimalarial resistance. In K. Chibale, M. Davies-
Coleman and C. Masimirembwa (eds), Drug Discovery in
Africa, pp. 301-324. Germany: Springer Heidelberg New
York Dordrecht London. ISBN 9783642281747.
Articles in peer-reviewed Journals
Abdullahi, L., Hussey, G.D., Mahomed, H. and Wiysonge,
C.S. 2012. Public stewardship of private for-profit care in
low-and middle-income countries. Cochrane Database of
Systematic Reviews, 5: 1-26.
Ahonkhai, A.A., Noubary, F., Munro, A., Stark, R., Wilke, M.,
Freedberg, K.A., Wood, R. and Losina, E. 2012. Not all are
lost: interrupted laboratory monitoring early death, and
loss to follow-up (LTFU) in a large South African treatment
program. PLoS One, 7(3): e32993.
Airoldi, F., Faglia, E., Clerici, G. and Latib, A. 2012. Bailout
directional atherectomy for side branch salvage following
subintimal recanalization of infragenicular arteries. Vasa-
European Journal of Vascular Medicine, 41: 292-294.
Akinyi, M., Dandara, C., Gamieldien, J. and Heckmann,
J.M. 2012. Association of transforming growth factor
beta-1 (TGFB1) regulatory region polymorphisms with
myasthenia gravis-related ophthalmoparesis. Journal of
Neuroimmunology, 246: 96-99.
Akl, E., Kennedy, C., Konda, K., Caceres, C., Horvath,
T., Ayala, G., Doupe, A., Gerbase, A., Wiysonge, C.S.,
Segura, E.R., Schunemann, H.J. and Lo, Y.R. 2012. Using
grade methodology for the development of public health
guidelines for the prevention and treatment of HIV and
other STI’s among men who have sex with men and other
transgender people. BMC Public Health, 12:386.