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UCT RESEARCH REPORT 2012
Dr Frederic Douelle
Hit to lead and lead optimization medicinal chemistry
progression of antimalarial hits.
Dr Marlene Elizabeth Espinoza Moraga
Hit to Lead and Lead Optimization Medicinal Chemistry
Progression of Antimalarial Hits
Dr Tzu-Shean Feng
New generation of combined drugs to fight tuberculosis
Dr Riedaa Gamieldien
Hybrid algorithms, Hybrid Architecture on a distributed
highly available Protein Server for Structure Prediction,
Functional Exploration and Gene Signatures
Dr Richard Klaus Gessner
New generation of combined drugs to fight tuberculosis
Dr Diego Gonzalez-Cabrera
Hit to lead and lead optimization medicinal chemistry
progression of antimalarial hits.
Dr Emma Hager
The Synthesis of Water-Soluble Metallodendrimers for Use
as Catalysts in Olefin Transformation Reactions
Dr Ze Han
Hit to lead and lead optimization medicinal chemistry
progression of antimalarial hits.
Dr Ahmad Husain
Crystal engineering of large supramolecular assemblies
and metal-organic frameworks
Dr Claire le Manach
Hit to lead and lead optimization medicinal chemistry
progression of antimalarial hits.
Dr Stefan Louw
Synthesis of novel artemisinin hybrid anti-malarial drugs.
Dr Banothile Charity Events Makhubela
Development of Water-Soluble Metallodendrimers for
Biphasic Catalysis and as Novel Bioorganometallic Drugs
Dr Jestin Mandumpal
Development of coarse grain molecular dynamics software
for protein folding
Dr Maia Meurillon
New generation of combined drugs to fight Tuberculosis.
Dr Grace Mugumbate
Application of in silico Tools to the discovery of novel anti-
infective agents.
Dr Dubekile Nyoni
The Design and Development of Novel Ruthenium,
Rhodium and Iridium Dendritic Multinuclear Complexes
for Use in Medicinal Bio- and Nanotechnology
Paquet,Tanya
Hit to Lead and Lead Optimization Medicinal Chemistry
Progression of Antimalarial Hits
Dr Marivel Samipillai
Selectivity in Host-guest Systems
Dr Rajni Sharma
Synthesis of N domain selective ACE inhibitors.
Dr Kawaljit Sigh
Towards the synthesis of reversed anti-tuberculosis agents
and hybrid bacterial efflux pump inhibitors
Dr Candice Soares De Melo
New generation of combined drugs to fight tuberculosis
Contact details
Tel: +27 21 650 2446
Fax: +27 21 650 5195
e-mail: shanaaz.manie@uct.ac.za
web: http://www.uct.ac.za/depts/cem
Research output
Edited books
Chibale, K., Davies-Coleman, M. and Masimirembwa, C.
(eds) 2012. Drug Discovery in Africa. 429pp. Germany:
Springer Heidelberg New York Dordrecht London. ISBN
9783642281747.
Chapters in books
Báthori, N.B. and Nassimbeni, L.R. 2012. Conformational
flexibility and selectivity in host-guest systems. In E.R.T.
Tiekink and J. Zukerman-Schpector (eds), The Importance
of Pi-Interactions in Crystal Engineering: Frontiers in Crystal
Engineering, pp. 125-141. United Kingdom: John Wiley
and Sons, Ltd. ISBN 9780470688274.
Guantai, E.M. and Chibale, K. 2012. Natural product-
based drug discovery in Africa: the need for integration
into modern drug discovery paradigms. In K. Chibale,
M. Davies-Coleman and C. Masimirembwa (eds), Drug
Discovery in Africa, pp. 101-126. Germany: Springer
Heidelberg New York Dordrecht London. ISBN
9783642281747.