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Faculty of Science
copolymerization. 188pp. Supervised by Hutton, A.T. and
Coville, N.J.
Njogu, P. 2012. Molecular hybrids of N-benzol-(2R,
3S)-3-phenylisoserine with antimalarial scaffolds: design,
synthesis and biological evaluation for antitumoural and
antiplasmodial activity. 209pp. Supervised by Chibale, K.,
Hendricks,D. and Jardine, A.
Nsumiwa, S. 2012. Synthesis and investigation of quinoline
based beta-haematin formation inhibitors as potential
antimalarials. 180pp. Supervised by Egan, T.J. and
Chibale, K.
Pillay, P. 2012. Antiplasmodial neolignans from trema
orientalis-identification, synthesis and analogue generation.
228pp. Supervised by Chibale, K. and Maharaj, V.
Ramsout, R. 2012. Investigation of the in vivo and in vitro
effects of some herbal preparations on risk factors for
calcium oxalate stone disease. 182pp. Supervised by
Rodgers, A.L.
Thelingwani, R.S. 2012. Integration of in silico and in vitro
ADMET properties in lead identification and optimization
of compounds for the treatment of parasitic diseases.
204pp. Supervised by Chibale, K., Masimirembwa, C. and
Smith, P.
Tukulula, M. 2012. The application of the multi-component
reaction (MCR) strategy in the design and synthesis of
new antiplasmodial and antimycobacterial agents. 239pp.
Supervised by Chibale, K.
Watermeyer, N.D. 2012. Design and synthesis of potential
inhibitors of enzymes involved in the biosynthesis and
utilisation of mycothiol. 204pp. Supervised by Gammon,
D.W. and Steenkamp, D.
Wewers, F.P. 2012. Transition metal complexes of
dithiolenes: structural, spectroscopic, electrochemical
and computational studies. 214pp. Supervised by
Hutton, A.T.
Zheng, F. 2012. Olefin oligomerization reactions: theoretical
studies using cyclometallated palladium(II) catalysts and
experimental studies on platinum(II) analogues. 218pp.
Supervised by Moss, J.R., Hutton A.T., Mapolie, S.F. and
van Sittert, C.G.C.E.
Master’s degrees (by research)
Adams, M. 2012. Mono- and multinuclear PGM complexes
containing thiosemicarbazones: synthesis, characterisation
and antiplasmodial evaluation. MSc. 127pp. Supervised by
Smith, G.S. and Chibale, K.
Bowden, G.D. 2012. Novel acyclic nucleotide phosphonates
against RNA viruses. MSc. 115pp. Supervised by Hunter, R.
Matsinha, L.C. 2012. Design, synthesis and characterisation
of water-soluble ruthenium arene complexes and their
evaluation as aqueous biphasic hydroformylation catalysts.
MSc. 98pp. Supervised by Smith, G.S. and Mapolie, S.F.
Nengwekhulu, T.M. 2012. Computer simulations of a
chromatographic column used in the separation of
platinum group metal chlorinated complexes. MSc. 95pp.
Supervised by Naidoo, K.J. and Venter, G.A.
Department of Computer
Head of Department: Associate Professor
Sonia Berman
Departmental Profile
The Department’s main research themes are Information
and Communication Technology for Development (ICT4D)
and High Performance Computing( HPC). ICT4D is a multi-
disciplinary field which looks at the design and creation
of computer systems for the developing world. These
systems could cover any sub-discipline of computing, such
as the Internet of Things, virtual environments, security,
interaction design, artificial intelligence and information
retrieval. However they differ in that design constraints
for the developing world are different: power is limited,
networks scarce, users can be illiterate, etc. ICT4D deals
with the creation of ICT solutions that address defined
developmental and social challenges like education,
medical care, identity and human dignity. High Performance
Computing is an enabling technology that seeks to improve
the performance of computing applications. For example,
a carbohydrate simulation might be reduced from years to
months, or digital 3D content produced in real time rather
than requiring minutes to generate. A major theme of this
HPC research is improving the speed of discipline-specific
computational solutions.
The Department has two research centres and several
research laboratories. The Collaborative Visual Computing
Laboratory works in five main areas: procedural modelling,
geometric compression, graphical simulation, virtual
environments and computer games. The Digital Libraries
Laboratory covers information storage and retrieval,
including multilingual retrieval and cultural heritage